Grade III Proximal Humerus GCT Treated with Excision and Reconstructed with Megaprosthesis Augmented with Prolene Mesh- A Case Report
Vol 06 Issue 1 | January 2025 | page: 22-25 | Nirmal Chandra Mohapatra, Rajesh Rana, Eshaan Mishra, SK Gulshane Sohel, Soumitesh Sibananda Das
DOI: https://doi.org/10.13107/ojot.2025.v06.i01.68
Received 30/03/2024; Reviewed 26/04/2024; Accepted 11/11/2024; Published 10/01/2025
Authors: Nirmal Chandra Mohapatra [1], Rajesh Rana [1], Eshaan Mishra [1], SK Gulshane Sohel [1], Soumitesh Sibananda Das [1]
[1] Department of Orthopaedics, SCB Medical College and Hospital, Cuttack, Odisha, India.
Address of Correspondence
Dr. Eshaan Mishra
Senior Resident, Department of Orthopaedics, SCB Medical College and Hospital, Cuttack, Odisha, India.
Email: eshaanmishra271@gmail.com
Abstract
Background: Giant cell tumor( GCT ) of bone is a benign yet locally aggressive tumor affecting the epiphysis of long bones. Proximal humerus involvement is uncommon and presents significant reconstructive challenges, particularly in Campanacci Grade III lesions with pathological fracture.
Case Presentation: A 54-year-old female presented with pain, swelling, and inability to lift her left upper limb. Imaging revealed an expansile lytic lesion of the proximal humerus with pathological fracture. Core biopsy confirmed GCT. The patient received neoadjuvant denosumab followed by en-bloc resection and reconstruction using a proximal humerus tumor prosthesis with capsular augmentation using prolene mesh.
Results: At 2-year follow-up, the Musculoskeletal Tumor Society (MSTS) score improved from 41% preoperatively to 84%. Active abduction was 35°. There was no evidence of infection, implant loosening, or recurrence.
Conclusion: Wide resection with mesh-augmented tumor prosthesis reconstruction provides reliable local control and satisfactory functional outcome in aggressive proximal humerus GCT with pathological fracture.
Keywords: Giant cell tumor , Proximal humerus,Pathological fracture
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| How to Cite this Article: Mohapatra NC, Rana R, Mishra E, Sohel SKG, Das SS.Grade III Proximal Humerus GCT Treated with Excision and Reconstructed with Megaprosthesis Augmented with Prolene Mesh- A Case Report. The Odisha Journal of Orthopaedics and Trauma| January 2025; 06;01:22-25. https://doi.org/10.13107/ojot.2025.v06.i01.68 |
